The first full weekend of college football is winding down with two absolute must-watch matchups on Sunday, featuring four teams making their season debuts! Louisville and Ole Miss are set to clash in Nashville in the day’s only battle between ranked teams, while Notre Dame and Wisconsin will take the field at legendary Lambeau Field later tonight. Our pals at BetOnline.ag are back with some killer picks, and we’re zeroing in on the spread for both of these showdowns, trying to finish this opening weekend strong!
Rebels Ready to Roll With a Returning Star
Look, Ole Miss is being asked to win by a touchdown against Louisville, and honestly, we’re totally comfortable laying those points. Why? Continuity, baby! Trinidad Chambliss is back under center after an insane season where he ripped off 3,937 yards, 22 touchdowns, and only three interceptions last year. This guy led Ole Miss all the way to the College Football Playoff semifinals, and he’s not alone. Running back Kewan Lacy, who put on a show last year jumping over defenders like he did against LSU back in September of 2025 when Ole Miss beat them 24-19, is also returning. Lacy piled up a mind-blowing 1,567 yards and a school-record 24 rushing touchdowns! That’s just unfair, man.
Louisville’s got Isaac Brown, who averaged 8.8 yards per carry in an injury-shortened 2025, so he’s dangerous. But their passing game? Totally unproven. Ohio State transfer Lincoln Kienholz is stepping in as a full-time starter for the first time, and he’s only got 250 career passing yards and one touchdown to his name. The Cardinals absolutely have talent to make this competitive, but Chambliss just gives Ole Miss a huge, colossal advantage in this season opener. With all the unknowns floating around, expect the Rebels to steadily pull away as the game gets deeper and absolutely cover that 6.5-point spread.
Notre Dame’s Domination Awaits Wisconsin’s Struggling Offense
Over at Lambeau, the Notre Dame Fighting Irish are favored by a hefty 21 points against Wisconsin. Wisconsin’s defense might keep things respectable early on, sure. But their offense? Oh man, they’ve got a seriously long way to go. Last season, they averaged a measly 12.8 points per game, scoring 10 points or fewer in seven different games! That leaves almost zero room for error, especially when you’re going up against one of the best teams in the country. Old Dominion transfer Colton Joseph could bring some much-needed playmaking pop, but he’s making a huge jump in competition and debuting in a brand-new offense. That’s a tough ask, man.
Notre Dame, on the other hand, has way fewer question marks, especially at quarterback. CJ Carr is back after a killer first season as a starter, throwing for 2,741 yards and 24 touchdowns. These Irish weren’t just winning last year, they were dominating. They won eight games by more than 20 points! Wisconsin’s offense is just not equipped to hang with that kind of firepower for four quarters. Expect Notre Dame to come out swinging and hit that -21 spread easily.
This article was created with AI assistance and published under Seattle On Tap’s editorial standards. See our Editorial Policy.
Originally reported by Yahoo Sports.
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